You have a known hypersensitivity to norethisterone or to any of the excipients
You are pregnant or suspect that you are.
You have a presence or history of severe hepatic disease as long as liver function values have not returned to normal
You have undiagnosed genital bleeding
You have any previous idiopathic or current thromboembolism (deep vein thrombosis, pulmonary embolism).
You have an active or recent arterial thromboembolic disease (e.g. angina, myocardial infarction).
You have porphyria
You have epilepsy.
You have asthma.
You have cardiac dysfunction.
You have renal dysfunction
You have diabetes mellitus with vascular involvement
You have rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption
You are taking other sex hormones, including contraception
You are taking inducers of drug-metabolising enzymes, especially cytochrome P450 enzymes, including: anticonvulsants (e.g. phenobarbital, phenytoin, carbamazepine) and anti-infectives (e.g. rifampicin, rifabutin, nevirapine, efavirenz, tetracyclines, ampicillin, oxacillin and co-trimoxazole)
You are taking ritonavir and nelfinavir
You are taking herbal preparations containing St John s Wort (Hypericum Perforatum)
You are taking Aminoglutethimide
You are taking Ciclosporin
You are lactating
You have a presence or a history of prodromi of a thrombosis (e.g. transient ischaemic attack, angina pectoris)
You have a high risk of venous or arterial thrombosis
You have previous or existing liver tumours (benign or malignant)
You have known, past or suspected sex hormone-dependent malignancies, including breast or genital tract carcinoma
You have a history of migraines with focal neurological symptoms
History during pregnancy of idiopathic jaundice, severe pruritus, or pemphigoid gestationis
You have untreated endometrial hyperplasia
You have an active trophoblastic disease (until return to normal of urine- and plasma gonadotrophin concentration) – seek specialist advice. Patients should not use norethisterone after a recent evacuation of a hydatiform mole
You are taking nbsp;Anticoagulants
You are taking Griseofulvin
You are taking Amprenavir, taking Selegiline, taking Tizanidine