Migraine Treatment


Sumatriptan is a medicine to treat migraines and cluster headaches. It does not prevent these conditions. To read more about the use of Sumatriptan and how it works please click here.

Reasons for inclusion

  • You are over 18 years of age, and under 65 years of age, presenting with migraine (the diagnosis of migraine must be clear), including menstrual migraine (i.e. migraine without aura that occurs between 3 days prior and up to 5 days post onset of menstruation)

Reasons for exclusion

  • You under 18 years of age
  • You are over 65 years of age
  • You have a hypersensitivity to sumatriptan, sulphonamides, or to any of the excipients
  • You are pregnant or breastfeeding
  • You are presenting with any of the following (red flag): If a serious cause of headache is suspected, If the person is in severe, uncontrolled status migrainosus (migraine lasting for more than 72 hours), A complication of migraine has developed (for example migraine has become chronic), Diagnosis of migraine is uncertain
  • You have any of the following : Liver disease, Kidney disease, History of myocardial infarction, or have ischaemic heart disease, coronary vasospasm (Prinzmetal’s angina), peripheral vascular disease, or symptoms, or signs consistent with ischaemic heart disease, History of cerebrovascular accident (CVA), or transient ischaemic attack (TIA), Hypertension,
  • Hemiplegic, basilar, or ophthalmoplegic migraine, Diabetes, History of seizures or other risk factors which lower the seizure threshold, Rare hereditary problems of galactose-intolerance, the Lapp lactase deficiency or glucose/galactose- malabsorptio (tablets contain lactose)
  • You are a heavy smoker
  • If you take any of the following: Ergotamine, or derivatives of ergotamine (including methysergide), any other ‘triptan, or 5, hydroxytryptamine1 (5-HT1) receptor agonist, Reversible (e.g. moclobemide), or irreversible (e.g. selegiline) monoamine oxidase inhibitors (MAOIs, or within 2 weeks of discontinuation of therapy with MAOIs, SSRI, or SNRI antidepressants,
  • Lithium, Nicotine replacement therapy, or St John’s Wort (Hypericum perforatum)