Reasons for inclusion

• Male patients over the age of 18 years, presenting with erectile dysfunction

Reasons for exclusion

• All medicines are contraindicated in those who have had hypersensitivity to the active ingredient, or to any of the excipients
• Men for whom sexual activity is inadvisable & nbsp
• Patients who have loss of vision in one eye because of non-arteritic anterior ischaemic optic neuropathy (NAION), regardless of whether this episode was in connection or not with previous PDE5 inhibitor exposure
• Patients who are taking alpha1 blockers
• Patients with severe renal impairment
• You have severe hepatic impairment & nbsp
• Patients with anatomical deformation of the penis (such as angulation, cavernosal fibrosis, or Peyronie’s disease) or in patients who have conditions which may predispose them to priapism (such as sickle cell anaemia, multiple myeloma, or leukaemia)
• Men using other treatments for erectile dysfunction
• Patients taking the following drugs: Inhibitors of CYP3A4, such as ketoconazole ritonavir, saquinavir, erythromycin, clarithromycin, itraconazole, and grapefruit juice; CYP3A4 inducers, such as rifampicin, phenobarbital, phenytoin, and carbamazepine; 5-alpha reductase inhibitors
• Patients under 18 years of age
• You are female
• If you are male with any cardiovascular disorders, including angina, heart failure, history of stroke and/or myocardial infarction, arrhythmias, hypotension, or hypertension
• If you have any known hereditary degenerative retinal disorders such as retinitis pigmentosa (a minority of these patients have genetic disorders of retinal phosphodiesterases)
• The film coating of the tablets contains lactose – these medicines should not be administered to men with rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption
• These medicines potentiate the hypotensive effects of nitrates, and their co-administration with nitric oxide donors (such as amyl nitrite), or nitrates in any form is therefore contraindicated
• If you are male and taking nicorandil or ritonavir